Di tahun 2016, ia pun debut dalam tayangan drama seris di tv kabel berjudul Chees in the Trap yang dibuat berdasarkan sebuah webtoon.
Tidak hanya itu, ia pun berpartisipasi mengisi OST drama itu dengan menyanyikan lagu Attraction.
Sejak itu ia pun semakin dikenal dan berhasil memenangkan penghargaan di ajang Baeksang Arts Award untuk Best New Actress.
Di tahun yang sama, ia bermain drama berjudul Guardian: The Lonely and Great God.
Baca: Drama Korea Guardian: The Lonely and Great God (Goblin)
Baca: Minho Shinee
Pada 2019, ia pun mendapat tawaran peran sebagai lawan main Lee Min Ho di dalam drama The King: Eternal Monarch.
Kim Go Eun kembali tampil di layar kaca lewat drama Yumi's Cell.
Hero (2020) - Seol-Hee
Tune in for Love (2019) - Mi-Soo
Hit-and-Run Squad (2019) - perempuan berambut lurus
Sunset In My Hometown (2018) - Sun-Mi
Canola (2016) - Hye-Ji
The Advocate: A Missing Body (2015) - Jaksa Jin Sun-Mi
Memories of the Sword (2015) - Seol-Hee
Coin Locker Girl (2015) - Il-Young
Monster (2014) - Bok-Soon
Neverdie Butterfly (2013) - Moon Soo-Yeon
Eungyo (2011) - Han Eun-Gyo
Baca: Drama Korea - The King: Eternal Monarch (2020)
Yumi's Cells (tvN-TVING / 2021) - Kim Yu-Mi
The King: Eternal Monarch (SBS / 2020) - Jeong Tae-Eul / Luna / pilot (ep.16) / Jeong Eun-Kyeong (ep.16) / Jeong Tae-Ra (ep.16) / Jeong Hyo-Jin (ep.16)
Guardian: The Lonely and Great God (tvN / 2016-2017) - Ji Eun-Tak
Cheese in the Trap (tvN / 2016) - Hong-Seol
Best New Actress ("Cheese in the Trap") - 2016 (52nd) BaekSang Arts Awards
Favorite Rookie Actor ("The Advocate: A Missing Body") - 2016 Korea Youth Film Festival
Popularity Award ("Coin Locker Girl") - 2015 Korean Film Actors' Guild Awards
Best New Actress ("Eungyo") - 2012 (4th) KOFRA Film Awards Ceremony
Best New Actress ("Eungyo") - 2012 (33rd) Blue Dragon Film Awards
Best New Actress ("Eungyo") - 2012 Korean Association of Film Critics Awards
Best New Actress ("Eungyo") - 2012 (49th) Daejong Film Awards